Invitrogen™ TSPY1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534483

Product Code. 15345411

Description

A suggested positive control is A-20 cell lysate. PA5-34483 can be used with blocking peptide PEP-1525.

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Specifications

• Antigen: TSPY1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TSPY1
• Gene Alias: cancer/testis antigen 78; CT78; DYS14; pJA923; testis specific protein, Y-linked 1; testis-specific Y-encoded protein 1; TSPY; TSPY1; TSPY1L; TSPY1S
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7258
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q01534
• Gene Symbols: TSPY1
• Immunogen: A 20 amino acid peptide near the carboxy terminus of human TSPY1L.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG