Invitrogen™ TSPAN8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599214

Product Code. 16643465

Description

Antibody detects endogenous levels of total TSPAN8.

TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Specifications

• Antigen: TSPAN8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tspan8
• Gene Alias: C76990; CO-029; CO-29; D6.1A; E330007O21Rik; tetraspanin 8; Tetraspanin8; tetraspanin-8; Tm4sf3; transmembrane 4 superfamily member 3; TSPAN8; Tspan-8; Tumor-associated antigen CO-029
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7103
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P19075
• Gene Symbols: Tspan8
• Immunogen: A synthesized peptide derived from human TSPAN8(Accession P19075), corresponding to amino acid residues F109-A159.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG