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Invitrogen™ TSN Polyclonal Antibody

Product Code. 12859292
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Quantity:
100 μg
Unit Size:
100µg
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12859292 100 μg 100µg
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Product Code. 12859292 Supplier Invitrogen™ Supplier No. PA521150

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat lung tissue lysate. PA5-21150 can be used with blocking peptide PEP-1264.

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSN
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Tsn
Gene Accession No. Q15631, Q62348
Gene Alias 2610034C24Rik; AU040286; BCLF-1; C3PO; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; TB-RBP; testis brain-RNA binding protein; testis/brain RNA-binding protein; testis/brain-RNA-binding protein; translin; TRSLN; Tsn
Gene Symbols Tsn
Host Species Rabbit
Immunogen A 20 amino acid peptide near the carboxy terminus of human Translin.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22099, 60381, 7247
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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