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Tryptase alpha/beta 1 Antibody (TPSAB1/1961) - Azide and BSA Free, Novus Biologicals™

Product Code. 18352570 Shop All Bio Techne Products
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Quantity:
100 μg
Unit Size:
100µg
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18352570 100 μg 100µg
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Product Code. 18352570 Supplier Novus Biologicals Supplier No. NBP275754

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Description

Mouse Monoclonal Antibody

Tryptase alpha/beta 1 Monoclonal antibody specifically detects Tryptase alpha/beta 1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin), Protein Array.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tryptase alpha/beta 1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone TPSAB1/1961
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 1-2 ug/ml
Formulation 10 mM PBS with No Preservative
Gene Accession No. Q15661
Gene Alias EC:3.4.21.59, epididymis secretory sperm binding protein, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase, TPS1, TPS2, TPSB1, TPSB2, tryptase alpha II, Tryptase alpha-1, tryptase beta I, tryptase beta-1, Tryptase beta-2, Tryptase I, tryptase II, tryptase-1, tryptase-2, tryptase-I, tryptase-III
Gene Symbols TPSAB1
Host Species Mouse
Immunogen Recombinant human Tryptase alpha/TPS1 protein fragment (around aa 115-233) (Exact sequence is proprietary) (Uniprot: Q15661)
Purification Method Protein A or G purified
Quantity 100 μg
Research Discipline Immunology, metabolism
Primary or Secondary Primary
Test Specificity This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Due to sequence identity this antibody will likely cross react with tryptase beta 2.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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