Invitrogen™ TRPM2 Polyclonal Antibody, DyLight™ 550

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA522880

Product Code. 13227188

Description

TRPM2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (F), IHC (P)

TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.

Specifications

• Antigen: TRPM2
• Classification: Polyclonal
• Conjugate: DyLight 550
• Gene: TRPM2
• Gene Alias: 9830168K16Rik; C79133; EC 3.6.1.13; EREG 1; EREG1; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTRPC2; LTrpC-2; MGC133383; NUDT9H; NUDT9L1; null; transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; Transient receptor potential melastatin 2; transient receptor potential melastatin family 2; transient receptor protein 7; Trp7; TRPC 7; TRPC7; TRPM 2; Trpm2; Trpm2-predicted; Trrp7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28240, 294329
• Content And Storage: 4°C, store in dark
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.83 mg/mL
• Formulation: 50mM sodium borate with 0.05% sodium azide
• Gene Accession No.: E9PTA2, Q91YD4
• Gene Symbols: TRPM2
• Immunogen: Synthetic peptide made to a C-terminal portion of the rat TRPM2 protein (within residues 1430-1507).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG