Invitrogen™ TRPC4AP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5111595

Product Code. 17139513

Description

Immunogen sequence: LIWRKHSASA LVLHGHNQNC DCSPDITLKI QFLRLLQSFS DHHENKYLLL NNQELNELSA ISLKANIPEV EAVLNTDRSL VCDGK Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Specifications

• Antigen: TRPC4AP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRPC4AP
• Gene Alias: 4833429F06Rik; C20orf188; D2Ertd113e; hypothetical protein; mFLJ00177; PPP1R158; protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; short transient receptor potential channel 4 associated protein; short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor potential cation channel subfamily C member 4 associated protein; transient receptor potential cation channel, subfamily C, member 4 associated protein; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; Trpc4ap; trpc4-associated protein; Trrp4ap; TRUSS; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26133
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TEL6
• Gene Symbols: TRPC4AP
• Immunogen: Recombinant Protein corresonding to Human TRPC4AP. Recombinant protein control fragment (Product #RP-107400).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG