TRPC4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16850955	Proteintech 21349-1-AP-20UL	20 μL
16840955	Proteintech 21349-1-AP-150UL	150 μL

Description

TRPC4 is a member of the canonical subfamily of transient receptor potential cation channels. TRPC4 forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in TRPC4 may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRPC4. The classical or canonical transient receptor potential (TRPC) channels are the subfamily most closely related to the founding member of the TRP family, the Drosophila TRP channel. TRPC channels have seven TRPC genes that encode the channel protein (TRPC1-7). Diseases associated with TRPC4 include Photosensitive Epilepsy.

Specifications

• Antigen: TRPC4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: O35119, Q9QUQ5, Q9UBN4
• Gene ID (Entrez): 22066, 7223, 84494
• Immunogen: TRPC4 Fusion Protein Ag15698
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TRPC4

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: hTrp 4, HTRP4, Trp related protein 4, TRP4, TRPC4
• Gene Symbols: Trpc4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody