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Invitrogen™ TRPC3 Polyclonal Antibody

Product Code. 12818372
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Quantity:
100 μg
Unit Size:
100µg
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12818372 100 μg 100µg
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Product Code. 12818372 Supplier Invitrogen™ Supplier No. PA520255

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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse heart tissue lysate. PA5-20255 can be used with blocking peptide PEP-0391.

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the 'canonical TRP' (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPC3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Trpc3
Gene Accession No. Q13507, Q9QZC1
Gene Alias hTrp3; hTrp-3; ion channel protein; mTrp3; Mwk; receptor-activated cation channel TRP3; SCA41; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor protein 3; Trcp3; Trp3; TRP-3; TRPC3; TrpC3c; trp-related protein 3; Trrp3
Gene Symbols Trpc3
Host Species Rabbit
Immunogen A 14 amino acid peptide from near the amino terminus of human TRPC3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22065, 7222
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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