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Trop2 (EGP-1) Monoclonal Antibody (MR54), PE, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£78.25 - £220.00
Specifications
| Antigen | Trop2 (EGP-1) |
|---|---|
| Clone | MR54 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | PE |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15537066
|
Affymetrix eBioscience
12-6024-42 |
100 Tests |
£220.00
100 tests |
Estimated Shipment: 18-06-2024 Log in to see stock. |
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|
15527066
|
Affymetrix eBioscience
12-6024-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: This MR54 monoclonal antibody reacts with human Trop-2, which is also known as Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) and EGP-1. This type I transmembrane glycoprotein is expressed on trophoblast (syncytiotrophoblast and cytotrophoblast), epithelial, and most human carcinoma cells. Trop-2 plays a role in calcium-mediated signaling. Trop-2 has also been reported as an oncogene, with expression being correlated with tumorigenesis, metastasis, and anchorage-independent growth. Applications Reported: This MR54 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MR54 antibody has been pre-titrated and tested by flow cytometric analysis of MCF7 cell line. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.Specifications
| Trop2 (EGP-1) | |
| Flow Cytometry | |
| PE | |
| Mouse | |
| Human | |
| 4070 | |
| IgG2a κ | |
| Affinity chromatography | |
| TACSTD2 |
| MR54 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P09758 | |
| TACSTD2 | |
| Primary | |
| Antibody |
For Research Use Only.