Invitrogen™ TrkC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595101

Product Code. 16314375

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Mouse Brain Tissue, U87 Cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

Specifications

• Antigen: TrkC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ntrk3
• Gene Alias: AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18213, 29613, 4916
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: Q03351, Q16288, Q6VNS1
• Gene Symbols: Ntrk3
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TrkC (172-186aa QLWQEQGEAKLNSQN).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG