Invitrogen™ TRIP13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA562728

Product Code. 15700522

Description

Immunogen sequence: SKWFSESGKL VTKMFQKIQD LIDDKDALVF VLIDEVESLT AARNACRAGT EPSDAIRVVN AVLTQIDQIK RHSNVVILTT SNITEKIDVA FVDRADIKQY IGPPSA Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.

Specifications

• Antigen: TRIP13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIP13
• Gene Alias: 16E1BP; 16E1-BP; 2410002G23Rik; D13Ertd328e; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; human papillomavirus type 16 E1 protein-binding protein; Pachytene checkpoint protein 2 homolog; PCH2; Thyroid hormone receptor interactor 13; thyroid receptor interacting protein 13; thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP13; TRIP-13
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15645
• Gene Symbols: TRIP13
• Immunogen: Recombinant protein corresponding to Human TRIP13. Recombinant protein control fragment (Product #RP-103146).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG