Invitrogen™ TRIP10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577107

Product Code. 15973615

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Specifications

• Antigen: TRIP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Trip10
• Gene Alias: AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 106628, 9322
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15642, Q8CJ53
• Gene Symbols: Trip10
• Immunogen: Recombinant full length Human TRIP10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG