Trimethylsilyl isocyanate, 94%

Product Code. 11420473

Brand: Thermo Scientific Alfa Aesar A12633.09

Description

CAS: 1118-02-1 | C4H9NOSi | 115.21 g/mol

Trimethylsilyl isocyanate is used in the preparation of 1-unsubstituted 4-(dialkylamino) imidazolin-2-ones. It finds application in the carbamoylation of aromatic hydrocarbons and alcohols. It is also used in the preparation of primary amides from Grignard reagents. Further, it is used in the synthesis of cyclic imides. It is also utilized for the synthesis of trifluoroacetyl isocyanate and cyclic imides. In addition to this, it is employed in the conversion of isocyanates to carbodiimides using cyclopentadienyl Mn(CO)₃ catalysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl isocyanate is used in the preparation of 1-unsubstituted 4-(dialkylamino) imidazolin-2-ones. It finds application in the carbamoylation of aromatic hydrocarbons and alcohols. It is also used in the preparation of primary amides from Grignard reagents. Further, it is used in the synthesis of cyclic imides. It is also utilized for the synthesis of trifluoroacetyl isocyanate and cyclic imides. In addition to this, it is employed in the conversion of isocyanates to carbodiimides using cyclopentadienyl Mn(CO)₃ catalysis.

Solubility
Miscible with ethers and o-dichlorobenzene.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents, acids, strong bases, alcohols and amines.

Specifications

Chemical Identifiers

• CAS: 1118-02-1
• Molecular Formula: C4H9NOSi
• Molecular Weight (g/mol): 115.21
• MDL Number: MFCD00001993
• InChI Key: NIZHERJWXFHGGU-UHFFFAOYSA-N
• Synonym: trimethylsilyl isocyanate, silane, isocyanatotrimethyl, trimethylsilylisocyanate, isocyanato trimethyl silane, trimethylisocyanatosilane, tmsisocyanate, tms isocyanate, tms-isocyanate, tms isocynate
• PubChem CID: 70696
• IUPAC Name: isocyanato(trimethyl)silane
• SMILES: C[Si](C)(C)N=C=O

• Melting Point: -49°C
• Density: 0.859
• Boiling Point: 90°C to 92°C
• Flash Point: −2°C (28°F)
• Odor: Acrid
• Refractive Index: 1.396
• Quantity: 10 g
• UN Number: UN2478
• Beilstein: 1744962
• Sensitivity: Moisture sensitive; May form a precipitate
• Solubility Information: Miscible with ethers and o-dichlorobenzene.
• Formula Weight: 115.21
• Percent Purity: 94%
• Chemical Name or Material: Trimethylsilyl isocyanate

Safety and Handling

Product Identifier

• Trimethylsilyl isocyanate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 2
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H331-Toxic if inhaled.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P311-Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : Trimethylsilyl isocyanate

SDS

RUO – Research Use Only