Invitrogen™ TRIM27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527603

Product Code. 13401737

Description

Recommended positive controls: K562, THP-1, HL-60, U87-MG, SK-N-SH, IMR32, rat testis. Predicted reactivity: Mouse (97%), Rat (96%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.

Specifications

• Antigen: TRIM27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM27
• Gene Alias: AW538890; Gm19403; ret finger protein; ret finger protein 1; RFP; RFP transforming protein; Rfp1; RING finger protein 76; RING-type E3 ubiquitin transferase TRIM27; RNF76; Trim27; tripartite motif containing 27; tripartite motif protein 27; tripartite motif protein TRIM27; tripartite motif-containing 27; tripartite motif-containing protein 27; Zinc finger protein RFP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19720, 291171, 5987
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.66 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P14373, Q62158
• Gene Symbols: TRIM27
• Immunogen: Recombinant protein encompassing a sequence within the center region of human TRIM27. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG