Invitrogen™ TRIM23 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597010

Product Code. 16579841

Description

Immunogen sequence: MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT; Positive Samples: PC-12, Mouse spleen, Mouse brain; Cellular Location: Endomembrane system, Golgi apparatus membrane, Lysosome membrane.

Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.

Specifications

• Antigen: TRIM23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM23
• Gene Alias: 6330516O20Rik; ADP-ribosylation factor domain protein 1; ADP-ribosylation factor domain protein 1 64kD; ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; AI450195; ARD1; Ard-1; ARF domain protein 1; ARFD1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; nucleotide binding protein; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; RNF46; TRIM23; tripartite motif containing 23; tripartite motif protein 23; tripartite motif protein TRIM23; tripartite motif-containing 23; tripartite motif-containing protein 23
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 373, 81002, 81003
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P36406, P36407, Q8BGX0
• Gene Symbols: TRIM23
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM23 (NP_0016471).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG