Trifluoromethanesulfonic acid, 98+%, Thermo Scientific Chemicals

Description

Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.

Solubility
Miscible with water, dimethyl sulfoxide, dimethyl formamide and acetonitrile.

Notes
Hygroscopic. Incompatible with strong oxidizing agents, strong bases, water and metals.

Specifications

• Melting Point: -40°C
• Density: 1.708
• Boiling Point: 161°C to 162°C
• Flash Point: None
• Odor: Pungent
• Linear Formula: CF₃SO₃H
• Refractive Index: 1.327
• Quantity: 50 g
• UN Number: UN3265
• Beilstein: 1812100
• Sensitivity: Hygroscopic
• Merck Index: 14,9676
• Solubility Information: Miscible with water,dimethyl sulfoxide,dimethyl formamide and acetonitrile.
• Formula Weight: 150.07
• Percent Purity: ≥98%
• Chemical Name or Material: Trifluoromethanesulfonic acid

Safety and Handling

Product Identifier

• Trifluoromethanesulfonic acid

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Substances and mixtures corrosive to metals Category 1
• Skin corrosion/irritation Category 1 B
• Specific target organ toxicity Category 3

Hazard Statement

• H290-May be corrosive to metals.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : trifluoro-methanesulphonic acid

RUO – Research Use Only