Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11465440	Thermo Scientific Alfa Aesar 044630.AE	100 mL
11455440	Thermo Scientific Alfa Aesar 044630.5Y	4 x 100 mL
11475440	Thermo Scientific Alfa Aesar 044630.AP	500 mL
11485440	Thermo Scientific Alfa Aesar 044630.AY	4 x 500 mL

Description

The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and ceramic compounds. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. It finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 76-05-1
• Molecular Weight (g/mol): 114.02
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N
• PubChem CID: 6422
• IUPAC Name: 2,2,2-trifluoroacetic acid

• Molecular Formula: C2HF3O2
• MDL Number: MFCD00004169
• Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
• ChEBI: CHEBI:45892
• SMILES: OC(=O)C(F)(F)F

Specifications

• CAS: 76-05-1
• Boiling Point: 72°C to 73°C
• Assay Percent Range: >99.5%
• MDL Number: MFCD00004169
• Beilstein: 742035
• Solubility Information: Miscible with water,ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
• SMILES: OC(=O)C(F)(F)F
• Molecular Weight (g/mol): 114.02
• ChEBI: CHEBI:45892
• Grade: HPLC
• Odor: Pungent
• Refractive Index: 1.284
• Vapor Pressure: 8mm Hg at 20°C

• Melting Point: -15°C
• Color: Colorless
• Molecular Formula: C2HF3O2
• UN Number: 2699
• Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N
• IUPAC Name: 2,2,2-trifluoroacetic acid
• PubChem CID: 6422
• Formula Weight: 114.02
• Density: 1.48 g/cm³ at 20°C
• Physical Form: Liquid
• Sensitivity: Hygroscopic
• Chemical Name or Material: Trifluoroacetic Acid, Water 0.1%

Safety and Handling

P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c

H290-H314-H332-H335

missing translation for 'dotInformation' : DOT Class: 8, Packaging Group: I

missing translation for 'einecsNumber' : 200-929-3

missing translation for 'rtecsNumber' : AJ9625000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• Trifluoroacetic acid

Signal Word

• Danger

Hazard Category

• Skin corrosion/irritation Category 1 A
• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 3

Hazard Statement

• H332-Harmful if inhaled.
• H314-Causes severe skin burns and eye damage.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P405-Store locked up.
• P501-Dispose of contents/container to .

RUO – Research Use Only