Trifluoroacetic Acid, 99%, Alfa Aesar™

Solvent, catalyst, strong non-oxidizing acid

Brand: Alfa Aesar

Manufacturer Part Number: A12198.22

UNSPSC: 12352101

Code: NEW

Additional Details:
Additional Details: CAS Number: 76-05-1 Weight: 0.01000kg

Quantity 100g

Product Code. 11404863

Quantity Price
1 £ 18.23 / 100g
Estimated Shipment date
from Supplier 03-05-2017
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  • Description and Specification
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Description and Specification

Chemical Identifiers

Chemical Name or Material Trifluoroacetic Acid
CAS 76-05-1
Physical Form Liquid
Assay Percent Range 99%
Molecular Formula CF3CO2H
Formula Weight 114.02


Formula Weight 114.02
Quantity 100g
Melting Point −15°C (5°F)
Boiling Point 72° to 73°C
Physical Form Liquid
Density 1.480
Chemical Name or Material Trifluoroacetic Acid
Assay Percent Range 99%
Molecular Formula CF3CO2H
CAS 76-05-1
Storage Note 1 Hygroscopic

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4

Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

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Technical documents

Safety and Handling