Invitrogen™ TRHR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575412

Artikelnummer. 15981935

Beskrivelse

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.

Tekniske data

• Antigen: TRHR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRHR
• Gene Alias: MGC141920; Thyroliberin receptor; thyrotropin releasing hormone receptor; thyrotropin-releasing hormone receptor; TRH receptor; TRH1 Receptor; Trhr; TRH-R; TRH-R1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22045, 25570, 7201
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P21761, P34981, Q01717
• Gene Symbols: TRHR
• Immunogen: Synthetic peptide corresponding to amino acids 250-300 of Human TRHR.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG