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Tranilast, Tocris Bioscience™
Antiallergic; inhibits inflammatory mediator release from mast cells
£516.19
Chemical Identifiers
CAS | 53902-12-8 |
---|---|
Molecular Formula | C18H17NO5 |
Molecular Weight (g/mol) | 327.34 |
MDL Number | MFCD00864787 |
InChI Key | NZHGWWWHIYHZNX-CSKARUKUSA-N |
Synonym | tranilast, rizaben, trans-tranilast, tranilastum, n-3,4-dimethoxycinnamoyl anthranilic acid, tranilastum inn-latin, tranilast usan:inn:jan, tranpro, unii-hvf50smy6e, rizaben tn |
PubChem CID | 5282230 |
ChEBI | CHEBI:77572 |
IUPAC Name | 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid |
SMILES | COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC |
Description
Antiallergic via inhibition of chemical mediator release from mast cells. Shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor. Inhibits TRPV2-mediated responses; binds to Aβ40 monomers and increases Aβ40 fibrillation.Chemical Identifiers
53902-12-8 | |
327.34 | |
NZHGWWWHIYHZNX-CSKARUKUSA-N | |
5282230 | |
2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid |
C18H17NO5 | |
MFCD00864787 | |
tranilast, rizaben, trans-tranilast, tranilastum, n-3,4-dimethoxycinnamoyl anthranilic acid, tranilastum inn-latin, tranilast usan:inn:jan, tranpro, unii-hvf50smy6e, rizaben tn | |
CHEBI:77572 | |
COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC |
Specifications
53902-12-8 | |
MFCD00864787 | |
NZHGWWWHIYHZNX-CSKARUKUSA-N | |
2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid | |
5282230 | |
327.34 | |
Tranilast |
C18H17NO5 | |
tranilast, rizaben, trans-tranilast, tranilastum, n-3,4-dimethoxycinnamoyl anthranilic acid, tranilastum inn-latin, tranilast usan:inn:jan, tranpro, unii-hvf50smy6e, rizaben tn | |
COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC | |
327.34 | |
CHEBI:77572 | |
>99% |
Safety and Handling
Recommended Storage : Store at Room Temperature