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Trametinib, MedChemExpress

Product Code. 16494338
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Product Code. 16494338 Supplier Medchem Express Supplier No. HY10999

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Description

MedChemExpress Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis.

Trametinib (GSK1120212

Specifications

Chemical Name or Material Trametinib
CAS 871700-17-3
Color White
Purity Grade Notes Research
Molecular Formula C26H23FIN5O4
Quantity 10 mg
Synonym GSK1120212 JTP-74057
Solubility Information DMSO : 25 mg/mL (40.62 mM; ultrasonic and warming and heat to 60°C)
SMILES CC(NC1=CC=CC(N(C2=O)C(C(C(N2C3CC3)=O)=C(N4C)NC5=CC=C(C=C5F)I)=C(C4=O)C)=C1)=O
Molecular Weight (g/mol) 615.39
Formula Weight 615.39
Percent Purity 98.08%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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