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Trametinib (DMSO solvate), MedChemExpress

Product Code. 16460667
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Product Code. 16460667 Supplier Medchem Express Supplier No. HY10999A

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Description

MedChemExpress Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis.

Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)

Specifications

Chemical Name or Material Trametinib (DMSO solvate)
CAS 1187431-43-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C28H29FIN5O5S
Quantity 50 mg
Synonym GSK-1120212 (DMSO solvate) JTP-74057 (DMSO solvate)
Solubility Information DMSO : 69 mg/mL (99.49 mM; Need ultrasonic)
SMILES CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
Molecular Weight (g/mol) 693.53
Formula Weight 693.53
Percent Purity 98.51%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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