Invitrogen™ TRAIL-R3 Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA551033

Product Code. 17958912

Description

TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Specifications

• Antigen: TRAIL-R3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: O14798
• Gene Symbols: TNFRSF10C
• Immunogen: Recombinant Human TNFRSF10C protein, Glu32-Thr244 (Accession #O14798).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: TNFRSF10C
• Gene Alias: Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; Decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor superfamily member 10c; TNF-related apoptosis-inducing ligand receptor 3; TNFRSF10C; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; UNQ321/PRO366
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 8794
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid