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Invitrogen™ TPT1 Recombinant Rabbit Monoclonal Antibody (10A9)
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Product Code. 17207193 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17207193 100 μL 100µL
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Product Code. 17207193 Supplier Invitrogen™ Supplier No. MA538315

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Rabbit Recombinant Monoclonal Antibody

This antibody has been tested in direct-ELISA.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPT1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 10A9
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.4
Gene TPT1
Gene Accession No. P13693, P63028
Gene Alias 21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
Gene Symbols TPT1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TCTP.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22070, 7178
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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