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TPM3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16877313 Shop All Proteintech Products
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150 μL
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150µL
20µL
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16877313 20 μL 20µL
16867313 150 μL 150µL
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Product Code. 16877313 Supplier Proteintech Supplier No. 107371AP20UL

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Description

Rabbit Polyclonal Antibody

TPM3 (tropomyosin 3) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal domit nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen TPM3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TPM3
Gene Accession No. P06753, P21107, Q63610
Gene Alias Gamma tropomyosin, hscp30, hTM5, NEM1, OK/SW cl.5, TM 5, TM3, TM30, TM30nm, TPM3, TPMsk3, TRK, tropomyosin 3, Tropomyosin 5, Tropomyosin alpha 3 chain
Gene Symbols Tpm3
Host Species Rabbit
Immunogen TPM3 Fusion Protein Ag1171
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117557, 59069, 7170
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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