Invitrogen™ TPH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA526185

Product Code. 13270309

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Specifications

• Antigen: TPH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tph2
• Gene Alias: ADHD7; AU043594; MGC119994; Neuronal tryptophan hydroxylase; NTPH; Tph2; TPRH; TRPH; Tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; tryptophan hydroxylase 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 121278, 216343
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q8CGV2, Q8IWU9
• Gene Symbols: Tph2
• Immunogen: KLH conjugated synthetic peptide between 168-193 amino acids from the central region of human TPH2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG