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TP0463518, MedChemExpress

Product Code. 16484578
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Product Code. 16484578 Supplier Medchem Express Supplier No. HY112144

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Description

MedChemExpress TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

Specifications

Chemical Name or Material TP0463518
CAS 1558021-37-6
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C20H18ClN3O6
Quantity 10 mg
Solubility Information DMSO : ≥ 125 mg/mL (289.47 mM)
SMILES ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2
Molecular Weight (g/mol) 431.83
Formula Weight 431.83
Percent Purity 98.02%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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