TP0463518, MedChemExpress

Product Code. 16484578

Brand: Medchem Express HY112144

Description

MedChemExpress TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

Specifications

• Chemical Name or Material: TP0463518
• CAS: 1558021-37-6
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₁₈ClN₃O₆
• Quantity: 10 mg
• Solubility Information: DMSO : ≥ 125 mg/mL (289.47 mM)
• SMILES: ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2
• Molecular Weight (g/mol): 431.83
• Formula Weight: 431.83
• Percent Purity: 98.02%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Metabolism-sugar/lipid metabolism

Research purposes only