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TOX Monoclonal Antibody (TXRX10), eFluor™ 660, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£124.00 - £311.00
Specifications
Antigen | TOX |
---|---|
Clone | TXRX10 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15500007
|
Affymetrix eBioscience
50-6502-80 |
25 μg |
£124.00
25µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15510007
|
Affymetrix eBioscience
50-6502-82 |
100 μg |
£311.00
100µg |
In Stock Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: This TXRX10 monoclonal antibody reacts with human and mouse TOX, which is also known as Thymocyte selection-associated HMG box protein. This DNA-binding nuclear factor is expressed in thymocytes, T lymphocytes, NK cells, and lymphoid tissue-inducer (LTi) cells. TOX expression in thymocytes is upregulated during beta-selection and positive selection. Studies using Tox knockout mice have demonstrated a critical role for TOX in CD4+ T cell development as a regulator of the CD4loCD8lo to CD4+CD8lo transition. Moreover, TOX has been shown to be involved in the development of NK and LTi cells. While its regulation remains unclear, TOX expression has been shown to be induced by calcineurin-mediated TCR signaling in thymocytes during positive selection. Applications Reported: This TXRX10 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This TXRX10 antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcriptin Factor Buffer Set (cat 00-5523) and protocol. Refer to Best Protocols- (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins). This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.
TOX Monoclonal antibody specifically detects TOX in Human, Mouse samples. It is validated for Flow Cytometry.Specifications
TOX | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1 | |
TOX | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
TOX |
TXRX10 | |
Flow Cytometry | |
eFluor 660 | |
Rat | |
Human, Mouse | |
O94900, Q66JW3 | |
252838, 9760 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.