Invitrogen™ Toralizumab Chimeric Recombinant Rabbit Monoclonal Antibody (IDEC-131 (Toralizumab))

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA548310

Product Code. 17981181

Description

Specificity: This antibody is a non agonistic antibody specifc for human CD40 ligand.

Toralizumab works by binding to interferon gamma, which prevents it from interacting with its receptors on immune cells. This blocks the downstream signaling pathways that lead to inflammation and tissue damage in autoimmune diseases. By blocking interferon gamma, toralizumab aims to reduce inflammation and prevent further tissue damage in affected individuals.

Specifications

• Antigen: Toralizumab Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P08729
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3855
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Inhibition Assays, Immunocytochemistry
• Clone: IDEC-131 (Toralizumab)
• Conjugate: Unconjugated
• Gene: KRT7
• Gene Alias: IDEC 131
• Immunogen: The original monoclonal antibody was generated by immunization with a soluble fusion protein of human gp39 (gp39-CD8).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ