Invitrogen™ TOP1 Recombinant Rabbit Monoclonal Antibody (SC69-03)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA532228

Product Code. 16385644

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

Specifications

• Antigen: TOP1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P11387, Q04750
• Gene Symbols: Top1
• Immunogen: Synthetic peptide within Human TOP1 aa 1-49.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: SC69-03
• Conjugate: Unconjugated
• Gene: Top1
• Gene Alias: Ab2-086; AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; TOP1; Top-1; TOPI; topoisomerase (DNA) I; Topoisomerase 1; type I DNA topoisomerase
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 21969, 7150
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid