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Invitrogen™ TOP1 Recombinant Human Monoclonal Antibody (K94015_11B11)

Product Code. 30824769
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50 μL
100 μL
Unit Size:
50µL
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30824769 50 μL 50µL
30827033 100 μL -
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Product Code. 30824769 Supplier Invitrogen™ Supplier No. MA564511

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Human Recombinant Monoclonal Antibody

Immunogen sequence: EHKGPVFAPP YEPLPENVKF YYDGKVMKLS PKAEEVATFF AKMLDHEYTT KEIFRKNFFK DWRKEMTNEE KNIITNLSKC DFTQMSQYFK AQTEARKQMS KEEKLKIKEE NEKLLKEYGF CIMDNHKERI ANFKIEPPGL FRGRGNHPKM GMLKRRIMPE DIIINCSKDA KVPSPPPGHK WKEVRHDNKV TWLVSWTENI Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%, Pig - 99%, Cynomolgus monkey - 100%.

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOP1
Applications ELISA
Classification Recombinant Monoclonal
Clone K94015_11B11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene Top1
Gene Accession No. P11387
Gene Alias Ab2-086; AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; TOP1; Top-1; TOPI; topoisomerase (DNA) I; Topoisomerase 1; type I DNA topoisomerase
Gene Symbols Top1
Host Species Human
Immunogen Recombinant human TOP1 (aa 221-420).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7150
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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