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Tocris Bioscience™ Tolvaptan
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Product Code. 18724848
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18724848 10 mg 10mg
18774529 50 mg 50mg
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Product Code. 18724848

Brand: Tocris Bioscience™ 5181/10

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166.60 GBP valid until 2026-03-31
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This item is not returnable. View return policy

Description

Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active

Tolvaptan is a potent and selective competitive vasopressin V2 receptor antagonist (Ki values are 0.06 and 12.3 nM for V2 and V1a receptors respectively). Decreases urine osmolality and increases serum sodium concentrations. Delays the onset of end-stage renal disease in a mouse model of polycystic kidney disease. Exhibits myocardial and renal protective effects in hypertensive heart failure rats. Orally active.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type Tolvaptan
Purity >98%
Molecular Weight (g/mol) 448.94
Inhibitors Tolvaptan

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