Tobramycin sulfate, Thermo Scientific™

A water-soluble aminoglycoside antibiotic

Brand:  Thermo Scientific Alfa Aesar J62995.03

Product Code. 15405279

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.

Solubility
Soluble in water (50 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Chemical Identifiers

• CAS: 49842-07-1
• Molecular Weight (g/mol): 565.59
• InChI Key: ZEUUPKVZFKBXPW-UHFFFAOYNA-N
• IUPAC Name: 4-amino-2-[(4,6-diamino-3-{[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]-6-(hydroxymethyl)oxane-3,5-diol; sulfuric acid

• Molecular Formula: C18H39N5O13S
• MDL Number: MFCD00133864,MFCD00133864
• PubChem CID: 54413
• SMILES: OS(O)(=O)=O.NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O

Specifications

• CAS: 49842-07-1
• Quantity: 1g
• MDL Number: MFCD00133864,MFCD00133864
• Solubility Information: Soluble in water (50mg/ml).
• SMILES: OS(O)(=O)=O.NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O
• Molecular Weight (g/mol): 565.59
• Formula Weight: 1425.41

• Color: White
• Molecular Formula: C18H39N5O13S
• Merck Index: 14,9490
• InChI Key: ZEUUPKVZFKBXPW-UHFFFAOYNA-N
• IUPAC Name: 4-amino-2-[(4,6-diamino-3-{[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]-6-(hydroxymethyl)oxane-3,5-diol; sulfuric acid
• PubChem CID: 54413
• Chemical Name or Material: Tobramycin sulfate