Invitrogen™ TNK1 Monoclonal Antibody (E.359.10)

Rabbit Monoclonal Antibody

Brand:  Invitrogen™ MA514860

Product Code. 11524831

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other related proteins.

TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.

Specifications

• Antigen: TNK1
• Classification: Monoclonal
• Concentration: 27.4 mg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: Q13470
• Gene Symbols: TNK1
• Immunogen: Synthetic peptide corresponding to the sequence around Pro97 of human TNK1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: E.359.10
• Conjugate: Unconjugated
• Gene: TNK1
• Gene Alias: CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8711
• Content And Storage: -20°C
• Form: Liquid