Invitrogen™ TNFAIP8L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589368

Product Code. 16557291

Description

Immunogen sequence: MESFSSKSLA LQAEKKLLSK MAGRSVAHLF IDETSSEVLD ELYRVSKEYT HSRPQAQRVI KDLIKVAIKV AVLHRNGSFG PSELALATRF RQKLRQGAMT ALSFGEVDFT FEAAVLAGLL TECRDVLLEL VEHHLTPKSH GRIRHVFDHF SDPGLLTALY GPDFTQHLGK ICDGLRKLLD EGKL; Positive Samples: Mouse thymus, Mouse spleen, Mouse small intestine.

TNFAIP8L2 - Tumor necrosis factor alpha-induced protein 8-like protein 2 (also known as TIPE2) acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. It is a negative regulator of Toll-like receptor and T-cell receptor functions. TIPE2 prevents hyperresponsiveness of the immune system and maintains immune homeostasis. It inhibits JUN/AP1 and NF-kappa-B activation. TIPE2 also promotes Fas-induced apoptosis.

Specifications

• Antigen: TNFAIP8L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tnfaip8l2
• Gene Alias: 1810019A08Rik; AW610835; inflammation factor 20; inflammation factor protein 20; RGD1310519; TIPE2; TNF alpha induced protein 8 like 2; TNF alpha-induced protein 8-like protein 2; Tnfaip8l2; TNFAIP8-like protein 2; TP8L2; Tumor necrosis factor alpha-induced protein 8-like protein 2; tumor necrosis factor, alpha induced protein 8 like 2; tumor necrosis factor, alpha-induced protein 8-like 2; tumor necrosis factor, alpha-induced protein 8-like protein 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 310663, 69769, 79626
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.87 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q6AYJ8, Q6P589, Q9D8Y7
• Gene Symbols: Tnfaip8l2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human TNFAIP8L2 (NP_0788512).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG