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TNF Mouse anti-Human, Alexa Fluor 700, Clone: MAB11, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 561023
Description
The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF- α ) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN- γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.
Specifications
| TNF | |
| Monoclonal | |
| 0.2mg/mL | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Recombinant Human TNF | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| MAb11 | |
| Alexa Fluor 700 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
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