Invitrogen™ TMPRSS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575286

Product Code. 15921815

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: TMPRSS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tmprss3
• Gene Alias: DFNB10; DFNB8; ECHOS1; Serine protease TADG-12; TADG12; TMPRSS3; Transmembrane protease serine 3; transmembrane protease, serine 3; transmembrane proteinase serine 3; transmembrane serine protease 3; tumor-associated differentially-expressed gene 12 protein; UNQ323/PRO382
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140765, 309665, 64699
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P57727, Q8K1T0
• Gene Symbols: Tmprss3
• Immunogen: Synthetic peptide corresponding to amino acids 420-460 of Human TMPRSS3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG