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Invitrogen™ TMEM88 Polyclonal Antibody

Product Code. 12819312
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Quantity:
100 μg
Unit Size:
100µg
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12819312 100 μg 100µg
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Product Code. 12819312 Supplier Invitrogen™ Supplier No. PA521164

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-21164 can be used with blocking peptide PEP-1278.

Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM88
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TMEM88
Gene Accession No. Q6PEY1, Q9D0N8
Gene Alias 2600017H02Rik; RGD1561781; TMEM88; TMEM88A; Transmembrane protein 88
Gene Symbols TMEM88
Host Species Rabbit
Immunogen A 19 amino acid peptide near the carboxy terminus of human TMEM88.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 497936, 67020, 92162
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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