Invitrogen™ TMEM252 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5140356

Product Code. 17874870

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: SNYRQVTESK GVLRHMLRQH LAHGALPVAT VDRPDFYPPA YEESLEVEKQ SCPAE Highest antigen sequence indentity to the following orthologs: Rat - 65%, Mouse - 69%.

Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf71 gene product has been provisionally designated C9orf71 pending further characterization.

Specifications

• Antigen: TMEM252
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM252
• Gene Alias: C9orf71; E030010A14Rik; RGD1359349; TMEM252; Transmembrane protein 252; transmembrane protein C9orf71; transmembrane protein C9orf71 homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 169693
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N6L7
• Gene Symbols: TMEM252
• Immunogen: Recombinant protein corresponding to Human TMEM252. Recombinant protein control fragment (Product #RP-99944).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG