TMEM24 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16864075	Proteintech 25507-1-AP-20UL	20 μL
16854075	Proteintech 25507-1-AP-150UL	150 μL

Description

This antibody detects TMEM24 protein with MW 70-100 kDa.

DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.

Specifications

• Antigen: TMEM24
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O14523
• Gene ID (Entrez): 9854
• Immunogen: TMEM24 Fusion Protein Ag21913
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: C2CD2L

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: C2CD2 like, C2CD2L, DLNB23, KIAA0285, TMEM24, Transmembrane protein 24
• Gene Symbols: C2CD2L
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody