Invitrogen™ TMEM185A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102247

Product Code. 16618724

Description

Antibody detects endogenous levels of total TMEM185A.

The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013].

Specifications

• Antigen: TMEM185A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM185A
• Gene Alias: BC023829; cDNA sequence BC023829; CXorf13; Ee3; erythropoietin-induced EST 3; FAM11A; family with sequence similarity 11, member A; fragile site, folic acid type, rare, fra(X)(q28) F; FRAXF; Protein FAM11A; Tmem185a; transmembrane protein 185A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 236848, 84548
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: A2AF53, Q8NFB2
• Gene Symbols: TMEM185A
• Immunogen: A synthesized peptide derived from human TMEM185A(Accession Q8NFB2), corresponding to amino acid residues D298-M348.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG