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TM5441, MedChemExpress

Product Code. 16422776
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Product Code. 16422776

Brand: Medchem Express HY101761

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Description

MedChemExpress TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence.

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence.

Specifications

Chemical Name or Material TM5441
CAS 1190221-43-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C21H17ClN2O6
Quantity 25 mg
Solubility Information DMSO : ≥ 300 mg/mL (699.59 mM)
SMILES ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1
Molecular Weight (g/mol) 428.82
Formula Weight 428.82
Percent Purity 98.18%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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