Invitrogen™ TM4SF18 Monoclonal Antibody (211116)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA523931

Product Code. 15543622

Description

This antibody stains human TM4SF18-transfected cells but not parent cells. Reconstitute at 0.5 mg/mL in sterile PBS.

Transmembrane 4 L Six Family Member 18 (TM4SF18) is a gene located on chromosome 11q12.3 that belongs to the transmembrane 4 L six superfamily, a group of proteins characterized by the presence of four transmembrane domains. TM4SF18 is expressed in various tissues and is involved in cellular processes such as cell adhesion, migration, and proliferation. As part of the tetraspanin family, TM4SF18 proteins play a role in organizing cellular membranes and facilitating interactions between cell surface receptors, impacting signaling pathways crucial for maintaining cellular functions and tissue homeostasis. Although TM4SF18's specific biological roles are still being elucidated, it has been implicated in tumorigenesis, where altered expression may influence cancer progression by modulating cell-cell communication and migration. Research into TM4SF18 aims to uncover its precise functions in health and disease, particularly its potential involvement in cancer biology and as a target for therapeutic interventions.

Specifications

• Antigen: TM4SF18
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q96CE8
• Gene Symbols: TM4SF18
• Immunogen: NS0 mouse myeloma cell line transfected with human TM4SF18 Met1-Ile201.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 211116
• Conjugate: Unconjugated
• Gene: TM4SF18
• Gene Alias: AAB5; L6D; TM4SF18; transmembrane 4 L six family member 18; transmembrane 4 L6 family member 18
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 116441
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized