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Invitrogen™ TM4SF18 Monoclonal Antibody (211116)

Product Code. 15543622
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Quantity:
100 μg
Unit Size:
100µg
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15543622 100 μg 100µg
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Product Code. 15543622 Supplier Invitrogen™ Supplier No. MA523931

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Description

Mouse Monoclonal Antibody

This antibody stains human TM4SF18-transfected cells but not parent cells. Reconstitute at 0.5 mg/mL in sterile PBS.

Transmembrane 4 L Six Family Member 18 (TM4SF18) is a gene located on chromosome 11q12.3 that belongs to the transmembrane 4 L six superfamily, a group of proteins characterized by the presence of four transmembrane domains. TM4SF18 is expressed in various tissues and is involved in cellular processes such as cell adhesion, migration, and proliferation. As part of the tetraspanin family, TM4SF18 proteins play a role in organizing cellular membranes and facilitating interactions between cell surface receptors, impacting signaling pathways crucial for maintaining cellular functions and tissue homeostasis. Although TM4SF18's specific biological roles are still being elucidated, it has been implicated in tumorigenesis, where altered expression may influence cancer progression by modulating cell-cell communication and migration. Research into TM4SF18 aims to uncover its precise functions in health and disease, particularly its potential involvement in cancer biology and as a target for therapeutic interventions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TM4SF18
Applications Flow Cytometry
Classification Monoclonal
Clone 211116
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene TM4SF18
Gene Accession No. Q96CE8
Gene Alias AAB5; L6D; TM4SF18; transmembrane 4 L six family member 18; transmembrane 4 L6 family member 18
Gene Symbols TM4SF18
Host Species Mouse
Immunogen NS0 mouse myeloma cell line transfected with human TM4SF18 Met1-Ile201.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116441
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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