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Invitrogen™ TM4SF1 Polyclonal Antibody

Product Code. 12849262
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12849262 100 μg 100µg
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Product Code. 12849262 Supplier Invitrogen™ Supplier No. PA521119

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-21119 can be used with blocking peptide PEP-1233.

TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TM4SF1
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TM4SF1
Gene Accession No. P30408, Q64302
Gene Alias 12A8 target antigen; H-L6; L6; L6 antigen; M3S1; Membrane component chromosome 3 surface marker 1; membrane component chromosome 3 surface marker 1 homolog; membrane component, chromosome 3, surface marker 1; membrane component, surface marker 1; TAAL6; TM4SF1; transmembrane 4 L six family member 1; transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1; tumor-associated antigen L6
Gene Symbols TM4SF1
Host Species Rabbit
Immunogen An 18 amino acid peptide near the amino terminus of human TM4SF1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17112, 295061, 4071
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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