Invitrogen™ TLX3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA583146

Código de producto. 16350105

Descripción

Immunogen sequence: APFEDAGSYS VNLSLAPAGV IRVPAHRPLP GAVPPPLPSA LPAMPSVPTV SSLGGLNFPW MESSRRFVKD RFTA Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).

Especificaciones

• Antigen: TLX3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLX3
• Gene Alias: homeo box 11-like 2; homeobox 11-like 2; homeobox protein Hox-11L2; Homeobox TLX-3; HOX11L2; Respiratory neuron homeobox protein; RGD1564190; RNX; T cell leukemia, homeobox 3; T-cell leukemia homeobox 3; T-cell leukemia homeobox protein 3; T-cell leukemia, homeobox 3; Tlx1l2; TLX3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30012
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43711
• Gene Symbols: TLX3
• Immunogen: Recombinant protein corresponding to Human TLX3. Recombinant protein control fragment (Product #RP-108335).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG