Invitrogen™ TLX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559372

Product Code. 15737231

Description

Immunogen sequence: GIDQILSGPE TPGGGLGLGR GGQGHGENGA FSGGYHGASG YGPAGSL Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 74%.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.

Specifications

• Antigen: TLX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLX2
• Gene Alias: Enteric neuron homeobox protein; Enx; homeo box 11-like 1; homeobox 11-like1; homeobox protein Hox-11L1; Homeobox TLX-2; hox11l; Hox11L.1; Hox11l1; NCX; Ncx1; neural crest homeobox protein; PMUR10F; T cell leukemia homeobox 2; T cell leukemia, homeobox 2; T-cell leukemia associated homeodomain protein; T-cell leukemia associated homeodomain protein Tlx3a; T-cell leukemia homeobox 2; T-cell leukemia homeobox protein 2; T-cell leukemia, homeobox 2; T-cell leukemia, homeobox 3a; Tlx1l1; Tlx1l2; Tlx2; tlx3a; Tlx-3a; tlxA; transcription factor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3196
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43763
• Gene Symbols: TLX2
• Immunogen: Recombinant protein corresponding to Human TLX2. Recombinant protein control fragment (Product #RP-98392).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG