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Invitrogen™ TLR9 Polyclonal Antibody

Product Code. 12808242
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Quantity:
100 μg
Unit Size:
100µg
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12808242 100 μg 100µg
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Product Code. 12808242 Supplier Invitrogen™ Supplier No. PA520203

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20203 can be used with blocking peptide PEP-0346.

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLR9
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Tlr9
Gene Accession No. Q9EQU3, Q9NR96
Gene Alias CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Gene Symbols Tlr9
Host Species Rabbit
Immunogen A peptide corresponding to 15 amino acids near the center of human TLR9.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 338457, 54106, 81897
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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