TLR8 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520056

Product Code. 12828272

Description

A suggested positive control is Daudi cell lysate. PA5-20056 can be used with blocking peptide PEP-0175.

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Specifications

• Antigen: TLR8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLR8
• Gene Alias: CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170744, 51311
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P58682, Q9NR97
• Gene Symbols: TLR8
• Immunogen: A peptide corresponding to 16 amino acids near the middle of human TLR8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG