Invitrogen™ Titin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552379

Product Code. 15740331

Description

Immunogen sequence: GTVSTSCYLA VQVSEEFEKE TTAVTEKFTT EEKRFVESRD VVMTDTSLTE EQAGPGEPAA PYFITKPVVQ KLVEGGSVVF GCQVGGNPKP HVYWKKSGVP LTTGYRYKVS YNKQTGECKL VISMTFADDA GEYT Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 27%.

Monoclonal Anti-Titin can be used for study of the elastic filaments within sarcomeric structures. It is also useful as a differentiation marker in the separation of rhabdomyosarcomas from other muscle tumors. By indirect immunofluorescence the antibody displays a typical striated staining pattern on frozen sections of chicken skeletal and cardiac muscle tissues. Stains the region of the A-I junction by indirect immunofluorescence. It shows a decoration line 0.05 mm from the end of the A band in electron micro-graphs. In immunoblotting using total extracts of chicken breast muscle the antibody reacts specifically with both bands of the titin doublet, and showed no reaction with nebulin.

Specifications

• Antigen: Titin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTN
• Gene Alias: 1100001C23Rik; 2.7.11.1; 2310036G12Rik; 2310057K23Rik; 2310074I15Rik; AF006999; AV006427; CMD1G; CMH9; CMPD4; Connectin; connectin/titin; D330041I19Rik; D830007G01Rik; DKFZp451N061; EOMFC; FLJ26020; FLJ26409; FLJ32040; FLJ34413; FLJ39564; FLJ43066; HMERF; L56; LGMD2J; mdm; MYLK5; rhabdomyosarcoma antigen MU-RMS-40.14; shru; structural muscle protein titin; titin; titin protein homolog; titin sequence3; TMD; TTN
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7273
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WZ42
• Gene Symbols: TTN
• Immunogen: Recombinant protein corresponding to Human Titin. Recombinant protein control fragment (Product #RP-89761).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG